Reminds me of the "Last Act of Defiance" cartoon in which a mouse, hanging from the talons of an eagle, angrily flips his middle finger up at the eagle as they fly away.
Maybe the lizard ate a poisonous bug, and it made him crazy. :)
Are the credits big enough? Can you all see them now? ;-) Normally, I don't post pics that have writing in BIG letters, but this was so unusual that I had to... - why would the lizard attack a giant?